Two children at village Ziapur of Burichang in Cumilla tested positive for COVID-19 on Thursday.
They were found infected just after four days of death of their grandmother from coronavirus infection.
Cumilla civil surgeon Abul Fazal Mir said that the children are seven and four years old.
Deputy civil surgeon Shahadat Hossain said Shaheda Khatun, grandmother of the children, died at Kurmitola General Hospital with coronavirus on Sunday.
Later, samples of the two children were sent to the Institute of Epidemiology Disease Control and Research (IEDCR) and both tested positive for the virus, Hossain said.
He said they will undergo treatment at home.
Burichang Upazila Nirbahi Officer (UNO) Mohamamd Imrul Hasan said the local administration put the village under lockdown on Tuesday after the children’s father Golam Mostafa and uncle Selim returned home from Dhaka.